In TychoBio we use moss as a green production platform for valuable plant metabolites and grow it in photo-bioreactors

Mosses are small flowerless plants that typically grow in dense green clumps or mats, often in damp or shady locations. There are approx. 12,000 species classified as Bryophyta. Bryophytes were allegedly the first plants to colonize the land about 480 million years ago. TychoBio works with the species Physcomitrella patens.

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The moss Physcomitrella patens has several properties that makes it an ideal host for the production of specialized plant metabolites. The genome of P. patens can be easily modified and new genes can be stably integrated. Whole biosynthetic pathways can be introduced and the moss can be engineered into producing useful compounds, like bio-pharmaceuticals, nutraceuticals and bio-plastic.

Our moss is grown in enclosed photo-bioreactors. Photo-bioreactors are sustainable and cost-effective: Moss can be cultivated in very simple conditions, and basically uses only light and CO2 to produce high-value plant metabolites.

In collaboration with University of Copenhagen we have developed a new technique to genetically modify moss, termed in vivo assembly. The technique greatly facilitates and speeds up the rate by which we are able to introduce biosynthetic pathways.  Learn more about the technology.